Dengue virus DENV is the causative agent of dengue fever and dengue hemorrhagic fever. The virus is endemic in over countries, causing over million infections per year. Dengue vaccine development is challenging because of the need to induce simultaneous protection against four antigenically distinct DENV serotypes and evidence that, under some conditions, vaccination can enhance disease due to specific immunity to the virus. While several live-attenuated tetravalent dengue virus vaccines display partial efficacy, it has been challenging to induce balanced protective immunity to all 4 serotypes.

Instead of using whole-virus formulations, we are exploring the potentials for a particulate subunit vaccine, based on DENV E-protein displayed on nanoparticles that have been precisely molded using Particle Replication in Non-wetting Template PRINT technology. Here we describe immunization studies with a DENV2-nanoparticle vaccine candidate. Antigen trafficking indicate that PRINT nanoparticle display of sRecE prolongs the bio-availability of the antigen in the draining lymph nodes by creating an antigen depot.

Our results demonstrate that PRINT nanoparticles are a promising platform for delivering subunit vaccines against flaviviruses such as dengue and Zika. Dengue virus DENV is transmitted by mosquitoes and is endemic in over countries, causing over million infections yearly.

Most infections are clinically unapparent, but under specific conditions, dengue can cause severe and lethal disease. This enhancement of infection complicates vaccine development and makes it necessary to induce protective immunity against all 4 serotypes. Since whole virus vaccine candidates struggle to induce protective immunity, we are developing a nanoparticle display vaccine approach. We have expressed, purified and characterized a soluble recombinant E-protein sRecE. Regardless of nanoparticle shape or size, particulation of sRecE enhances DENV specific IgG titers and induces a robust, long lasting neutralizing antibody response and by adsorbing sRecE to the nanoparticles, we prolong the exposure of sRecE to the immune system.

Nanoparticle display shows great promise in dengue vaccine development and possibly other mosquito-borne viruses like zika virus. Dengue virus DENVa member of the flaviviridae family, is the causative agent of dengue fever and dengue hemorrhagic fever. DENV and its Aedes sp.

Conoce a los 7 periodistas galardonados con los WASH Media Awards 2014

More than countries are endemic to DENV, but geographical expansion is expected to increase due to climate change, globalization of travel and trade and viral evolution [ 3 — 6 ]. Additionally, dengue is a complex disease resulting in a wide variety of clinical symptoms.

The majority of infections are very mild or clinically in apparent.Hab nigerian rice for sale,ga arha,ga dadi gashi kuma baya chabewa,15k ne kowani buhu muke saidawa,kuma muna aikawai ko ina a fadin dunia dik meso yakirawo wannan lambar Daga ofishin dr saude likitan mata. Dapatan muna lafia? To Allah ya taimakemu gabaki daya amin. Ayau nazomuku da abubuwa dadama wanda suke addaban mu ahalin yanzu,sanin kowa ne cewa ciwan sanyi yayimana katutu ajiki,kuma hakan ba qaramin illabane ga zamantakewarmu harma da auratayyarmu sabida duk macen datake tare da ciwan sanyi toh babu wani maganin matan dazai miki anfani ajiki duk kyansa kuma duk ingancinsa!

Haka zakila babu namijin dazai ji dadin yin ibadar aure d Abubuwan da mace mai ciwon sanyi zatayi shine. Dolene duk sanda zaki wanke underwears dinki kirinka jikashi acikin ruwa mai zafi da dan gishiri kadan domin kwayoyin ciwan su mutu kafin ki saka sabulun dettol maikyau kiwankeshi sannan ki shanyashi a rana idan ya bushe kuma kisaka iron kigoge.

Ga mai tambaya,ko karin bayani zaku iya aikomin sako ta wannan lambar kokuma kukirawoni awaya amman anayawan kirana cikin dare dan Allah akiyaye.

Idan har mutum yana bukata zai iya zuwa cafe da kusa dashi ya basu adreshin ayi masa don akwai ayyukan cigaba sosai a wannan kungiya kuma wannan register kyauta ne. By Auwal Azare. Assalamu alaikum jama'ar wannan gida barkanmu da shan ruwa, citta danya da kuke gani tanada matukar muhimmaci ajikin namiji wajen kara masa kuzari Lokacin saduwa, koda yake shi wannan hadin ba citta kadai ake bukata ba harda kiswatil hindi sahihin itace da yankin Asia wanda yanada kyau muyi bayani Akansa amma yanzu ganan hadin maza da akeyi, citta da kiswatil hindi za'a hada da abarba a Kirba a tace ruwan sai madara peak ta ruwa shikenan Ka gama hada madarar maza anasha sau biyu a dare daya, Kana shansa Babu kasala juriya da jajircewa tareda biyan bukatar iyali.

Kawai ki gurza kwakwa amma kafin nan saikin daka dabino da garin ridi wanda dama tuni kin soyashi sama hallau dama kin tafasa kanunfari kin tace ruwan to saiki zuba wadannan kayan gaba daya aciki sannan ki zuba nono me kyau da Zuma aciki saiki samu wajen ajiya me kyau ki ajiye kullum daga kinsha ruwa kada ki manta dashi. Daga Auwal Azare. Mace tun tana shekara 13 ko 14 take zama daya daga cikin masu jinin al ada har zuwa shekara 50 to daga nan malamai sun tabbatar hukunci jinin haila ya sauka akanta koda tanayi.

CIWON MARA Mata musamman wadanda basuda aure suna ciwon mara irin wannan kuma dattin maniyi ne domin ita mace maniyinta yana kasan nononta lokacinda sha awa tayi mata yawa zai dawo mararta idan be fitaba lokacin al ada saiya dinga mata ciwo. RIKICEWAR AL'ADA Koda yake ana samun canjawar lokacin zuwan al'ada kwanaki uku zuwa biyar to amma rikicewar sa alamune na matsala kuma ciwon sanyi infection shine kan gaba wajen kawo matsalar rikicewar al'adar mace, Ana samun matsalar aljanu suma sukan jawo matsalar rikicewar al'ada don haka me fama da wannan matsala ta nemi magani.

Ki rika tafasawa kina sha In sha Allahu al'ada zata daidai tu. Sannan 'Ya'yan Habbatus sauda idan ana taunawa ana hadiyewa in sha Allahu za'a samu lafiya. DAMINA KUSA domin dawoda ni,ima ko tabbatar da ita kankana zaki yanyanka kisamu kugiyar alawa wanda ake samu wajen masu sayarda alawa ki saka a tsakiyar kankanar ki saka kanunfari kibarshi ya dade idan ya jika saiki shanye KORAMA wannan kuma kankanar samanta zaki yanke ki saka kayan hadin aciki kibari ya dade duka ki shanye, yanda zakiyi bayan kin yanka saman saiki gurza kwakwa ki saka ruwan ki saka garin dabino da madara peak.

Jump to. Sections of this page.Www fimcoindustries com parts Snap simulator script pastebin Aprons at target Norscot diecast tahoe cds is your solution provider no matter the scope of your project, domestic or abroad. CDS is a subsidiary of Advantage Solutions Upgrade umbraco 7 to 8 Krizovatka smrti cely film Being single in your mid 30s Warning!

Unauthorized access to this system is forbidden and will be prosecuted by law!

Advantage solutions my oracle cds

By accessing this system, you agree that your actions can be monitored if unauthorized usage is suspected. Please browse all of our available job and career opportunities. Apply to any positions you believe you are a fit for and contact us today! Oracle account sign in. Username Username is usually your email address. Forgot Username? Password Forgot Password? Please enter your Username and Password ]. Have questions or concerns about your employment? You can get in touch with an HR Advisor by submitting a ticket via the Associate Service Center, or calling Advantage Solutions is the largest sales and marketing company in North America.

Check out our page for the latest news on company culture and careeradvice. Gforce carbon fiber driveshaft Khatri vs jatt How to fake ram in pc Bdo breath of the ashen dead The largest sales agency serving the club store channel, Advantage deploys a team of highly experienced, dedicated experts across Costco, Sam's Club and BJ's Wholesale Club stores.

Our vertical team provides best-in-class headquarter sales servicesadministrative supportanalytics and insights and retail services. My Oracle, New Delhi, India. So guys share your knowledge here and grow with new things []. My Oracle Support is a comprehensive repository of useful information, handbooks, catalogues, diagnostic tools, best practices, patches, and software updates, as well as many more resources.

My Oracle Support enables you to search Oracle's knowledge base, manage service requests SRs when you need help, download patches, interact in support communities, and take advantage of proactive capabilities for managing systems. Maximus s10 price in bangladesh [Lied at meps sf86Aem infinity 7 manual]. Management information. CDS — Canada.

This last name is invalid. Please enter a valid last name. Email Address.Post a Comment. All kind of Wal katha Sinhalen, if you want to search new Katha Visit now. Banku Akka Sinhala Wela-Wanacharaya www.

Jul 10, - sinhala wal katha aluth site eka Jul 30, - wal katha sinhala aluth panty katha lk hiru gossip,hiru gossip lanka hot news sinhala,hiru See more of Wal katha by logging into Facebook Wal katha Sinhalen danna be harsha godak ayata sinhala support krnne ne podi fns valata. Ithin mage amma hitiye rata mata aiya kenek hitiya akka badala hitiye AKKA 'mama me kiyanna.

Aluth -Wela- Katha2. Tika welawakin mata katha kala mehata anna Kumari akka adinne satin silk green skirt ekak. Dec 10, - Aluth wisthara thamai mn duken inne, kiyala. Eya gana katha karala wadak na kiwwa, mata kisima sathutak na, mn ahuwa ai a?

Dec 27, - Sinhala Wal Katha brother with his sister in the hotel. HoT Lanka Aluth Wal Katha Lokaya Mage 1st Expirions aka maheesha franendo's mobile blog story. Mar 10, - ayata age 6ka podi lamayek hitiya. Sinhalawalforum - Popular Tags sinhalawal forum. Translate this page.

Podi Kale Wal Katha. Podi Kale Wal Katha. Feb 8, - Tag: chu. Eha gedara akka Mama kiwe ne, Tika welawakin lamaya nidagatta, Akka Hattayath Bima Sinhala wal katha - VidsShare www. Badima 1 watch video chamalka nangi watch video Sinhala Wal Katha Aluth Largest Sinhala Wela Katha Collection Stay with us for You may Ape Aluth Gedara 1. Find keywords like " wal katha ", " sinhala wal katha ", "hukana katha", "peperonity wal katha ", "gay wal katha ", and " sinhala wal katha amma".

Sinhala Parana Wal Katha 3. Sinhala parana wal katha aluth kolla ekka indiddi kollata ahuwela funny Related Posts to new sinhala wal katha - Online Backup www.Saturday, April 29, Kela parak mage pukata gahala.

Topa thiyala athulata thada kala. Ahhhhhhhhhhh mata kediri geuna. Mage bellen alla gaththa ayya eka digta puke arinna gaththa. Ayyage polla pukata loku wedi kiyala mata therune tika welwak yanakota.

Western Province Aesthetic Resort (NADA)

Ayya mawa sofa ekata thada krna pukata gehuwa. Ayyage ata deka mage puke thus thus gala wadinawa. Ayyage phone eka ring wena saddayak awa. Kawru hari disturb karanawa ban. Ayya puke payya thyagena phone eka gaththa. Hello, babe.

I'm at home right now. You wanna come now. Oh no babe I'm with a friend of mine. C u tomorrow. Ayya phone eka thyla polla puken eliyta gaththa. Kawdda ayye a?? Man ahuwa. American baduwak ban. Ada reta ape gedra enna ahnawa. Man ha kiyala. Ayyage lagta ghn papuwa atha gewa. Mawa puken ussala aran ayya wada gaththa. Umba mara cute ban. Mage payya da ganin mage wasthu umbe bola pukata.

Ayya mage kana hapna gamn kiwwa. Man ayyage topa puke thiya gaththa. Ayyage asama position eka. Mawa uda dada pukata hodata eriya winadi 5k withra. Mata badu yanna enawa ban. Mmh man ayyage polla tikak iruwa. Man ayyage thattam deka atha gewa. Mara hayyai. Khmada ban.

Hodaida ayyage payya. Ayye oya ki denekta hukla thynawada? Man ahuwe ayyage ata deka allana gaman. Kello nam ganan karanna beri thrmta hukla thynawa ban. Issara dubai innakota kollo gehuwa ekasiya ganata.Mage nama suresh wayasa awrudu 23i gdr ayath ekka athi una katha bahak dura diga gihin gdr atha arala Colombo walata avith dn awrudu 3 kata kitt Mn ithn dennata kittu karala poddk belma demma un dennatath kisima ganak na mn balanawa kiyala tika welawak yaddi un dennath ma ekka hina una nisa mn kisi chakithayak nethuwa denna gawata kittu karala katha kala denna ekka tikak katha karana kota un denna mata hodata fit una ithin mn nkmta ahuwa math oyala ekka film eka balanna set unata awl ndda kiyala un dennath ekata eka painma kemathi una nisa mn Matath meka amuthuma vidihe filling ekak genalla thibbe.

Mama gihilla bell eka gehuwama diwya avilla dora arala lassana hinavakin mawa pili aragena geta ada gaha gena giya supuni nm podi wedakata aliyat gihilla anna giya mn giye na oya anawa kiyal qwa nisama supunith hebei tika welawak yana kota ei mn hithanne oya kemathi thenaka ida gannako oayage thenak kiyala hitha gena mn oyat bonna bima ekak hada gena annam kiyagena diwya kussiay peththata giya.

Ithin mn eyalage bed ake peththakin ida gththa tika welawak yaddi diwya bima dekakuth hada gena avilla mata tikak ahata wenna ida gaththa mata eka bima ekak dila. Api tika welawak yana kaleka eka wal pal katha kara kara hitiya eka parata diwya eda film eka balpu eka gena kathja karann patan gththa.

Eya eka godak asawen rasa vinda wagema aken gdk vinoda una kiyala kiyana kota mn hituwe eya film eka gena wenna thi me katha karanne kiyala. Ath eya mata penna kakul deka udata aragena mage age gewena nogewena tharamata kakul deka thiyagena athullanna gththama thama mata therune eya mokak genada me katha karanne kiyala ithin math shanikawa bima eka peththakin thiyala diwayge eka kakulak athata arage yati pathul massage karanna patan gaththa tika welawak ahema karaddi diwyage hini kediriyak anawa kiyala mata ahuna.

Ithin diwya man me karan deta oya kemathida kiyala mn eyagen ahuwama eya hurubuhuti hinawk dala oluwa wenuwa. Mata theruna mage malli babatath ake filling eka denial tika tika alu gasala dala negitinna patan aragena kiyala. Eka paratama ahema kara kara hitapu diwya eyage mulu barama a kakulata dila mage bada udata neggama nm mata Kediri gewuna.

Ath diwyage ara lassana hinawa nethi karanna uwamanawk mata thibune nethi nisama man as deka piya gena a wedanawa iwasagena inna hitha gaththa. Oyata amaru na nda man gdk bara nane kiyala lassan hinawak dala magen ahuwath mama thamath eyage barata purudu wela hitiye nethi nisa mata katha kara ganna puluwn kmk thibbe na mn amaruwn husama allagena aluw wenuwe na kiyanna wage.

Eya mage bada uda hita gena thawamath samabrawa inna try karanawa kiyala mata theruna eya ekama thena kata bara dila inna nisa mage amaruwa anna annam wedi wela hini kediriyak pita wenna gaththe matath horenmai. Mage bada uda vinadi 3kta 4kata kittu welawa hita gena idala mage papuwa udata anna hadanne kiyala mata therune eyage sinidi kakul mage kamise assen papuwa uda ta ana kotai mama himita oluwa tikak vithra ussala eya diha beluwa mata eyage kapu kata kalisama wena kal pena eyage lassana suduma sudu kakul deka dekala thibba amaruwa kohen giyada kiyala hitha ganna beri una eyage adagena hitiya blouse ekath tika kota lihil ekak nisa eyage lassana hansa petaw denna penawa lawata wage.

Vinadi kihi pahayakata passer mn giya weda tiaka kara gena aliyata ana kota supunith avilla supuni mata hi kiyala kiyanwath ekkama wage mage as deka nikn nilankara vigena yanwa wage mata theruna mokuth hitha gannath kalin mawa kalanthe dala thibba athana apahu mata sihiya ana kota kello denna ekka mawa bed eka udata dala diwya mage sihiya ganna munta thattu karanawaman as ariyath thamath mage as wala dellak bedila wage nkm. Oya hodinda supuni magen ahuwa Mama dan na mata eka parata mkd une mn amaruwen a wachan tika pita karala eyalagen ahuwa Oya mage diha moda paththayek wage bala gena idala eka parata kalanthe dala wetuna kiyala supuni qwe hin wena gmn eka qwama nm matath eka partama hina giya.

Mama bed eka uda wadi unama diwya avilla mage gavinma wam peththe wadi una supuni mata tika ahata wenna dakunu peththata wenna ida gaththa ai oya aththatama kalanthe demme apahu diwya magen prashna kala Eka thama matath hitha ganna beri thamath a khma unath man hithanawa mn dn hodin samahara vita kellage lassana dekala wenna athi kiyala mn qwa yanthamata wage hina wela qwa Aththatam oyata nm hodat pissu oya mawa chatr kranna hadanawa boru kiyala supuni qwe hinawkuth dala.

Ahh ahhh diwya a tharam kola gena hithanaw wage kiyala supuni aphu vihilu karanna gththa apita. Hebei diwyata wada tikak vithra bara wedi unath mn sadde nethuwa hitiya nkm mage hithe meka gena kemeththak athi welawathda kiyala sekekuth mata awa. Oya hodin nda kiyala mage papuwa uda hita gena supuni magen ahuwa m now kiyala qwa Supuni adagena hitiye sudu pata kota sayak nisa eyage jangiyath penawa mata hodata ewa dekala mage paiya apahu kelin vigena anawa mata theruna.

Kiyala supuni mage diha balala hina una. Oyata dn nm kalinta wada asa athi nda kiyala diwya ahapu de aththa kiyala mata therune mage mallitath eka denial thibba nisai. Mn mokuth hitha ganna beruwa ahema inna kota supuni kiyanwa mkdda ane cuttak mage viluba lick karanna asa ndda ane kiyala ithin mn tak gala kata arala supunige viluaba hodata lewa kala uranna patan gththa.

A wena kota me kello denna karana dewal nisa sex karala gannawata wad athal ekak mata lebun kiyala mn hithanne nkm diwya loke inna wage hegimak mata athi wela thibbe mn kawadawath hithala thibbe na me wage lassana kello dennek mage aga uda hita gena me wage athal gani kiyala.Shafine da aka bude wa masoyan littatafan hausa wato Hausa Novels Blog a kyauta wanda muke kawo muku littatafai daga marubuta daban daban.

Barkanmu da ganin wata mai girma tare da fatan kuna cikin koshin lafiya. A yau na kawo muku yadda ake yin burodin ayaba. Za a iya gwada wa a lokacin yin buda baki ko kuma don yi wa bakin da aka gayyato shan ruwa. Bayan haka, a zuba bata kamar cokali biyu sannan a kwaba sosai. Sannan a fasa kwai biyu da wannan kwababben ayabar a cikin fulawar da aka yi masa hadin suga da sauransu.

Sai a gauraya don su kwabu. Kuma za a iya aika wa makwabta domin su dandana sabon salon burodi. A sha ruwa lafiya. Matashin saurayine mai kimanin shekaru 30, gashin kansa duk ya kudun dune, Launin fatarsa ya chanza saboda dattin dake jikinsa rigarsa duk ta yage, Farine amma saboda tsabar datti har farin yafara dishewa, fatar jikinsa dukta jeme saboda zafin rana hakama tufafin dake jikinsa, amma hakan bai hana kyan fuskarsa fita ba, kyankywane duk da cikin sigar hauka yake Read more.

Gidan Novels Hausa Novels. Email This BlogThis! Share to Twitter Share to Facebook. Muhammad Abba Gana. Burodin ayaba Barkanmu da ganin wata mai girma tare da fatan kuna cikin koshin lafiya. MAJNOON hausa love novels Matashin saurayine mai kimanin shekaru 30, gashin kansa duk ya kudun dune, Launin fatarsa ya chanza saboda dattin dake jikinsa rigarsa duk ta yage, Farine amma saboda tsabar datti har farin yafara dishewa, fatar jikinsa dukta jeme saboda zafin rana hakama tufafin dake jikinsa, amma hakan bai hana kyan fuskarsa fita ba, kyankywane duk da cikin sigar hauka yake Mutane uku ne a duniya 1.

Wasu kamar guba ne gudunsu akeyi. Wasu kamar magani suke, ba a nemansu sai ta baci. Wasu kuma kamar abinci suke, akullum dole a nemesu. Ya kai dan uwa mai daraja, kayi kokari ka zama cikin wadanda akullum ake nemansu saboda amfaninsu. Popular Tags Blog Archives. Talla a Gidan novels. Be With Me Technology. Guide Tricks Blog. Sai sahabbai RA sukace Menene Alharju? Bukhari ya ruwaito a


thoughts on “Ganan teacherge wahala 7

Leave a Reply

Leave a Reply

Your email address will not be published. Required fields are marked *